Predicting internal diseases in humans using machine learning: A systematic literature review

Authors

DOI:

https://doi.org/10.59247/jahir.v2i1.195

Keywords:

Artificial Intelligence, Classification, Internal Medicine, Literature Review, Machine Learning

Abstract

Human health is the main focus of clinical medicine, especially in understanding internal diseases involving the body's organs. Identifying and predicting disease at an early stage is essential to prevent the development of more severe disease. These challenges encourage using the latest technologies, especially machine learning techniques. This technology is used to ensure accurate disease predictions. The results of the research identified various types of internal diseases, including heart, kidney, lung and liver cancer, and highlighted the associated symptoms and risk factors. Several algorithms are used to classify internal diseases, including the classification of heart disease. The logistic regression algorithm is the most efficient, with accuracy results of 88.52%. Meanwhile, CHIRP kidney disease classification provides the most efficient results with an accuracy of 99.75%. MobileLungNetV2 has an accuracy of 96.97% for lung disease classification, and classification for liver disease produces the highest accuracy in logistic regression at 72.50%. Machine learning in disease prediction significantly contributes, especially in increasing accuracy and efficiency in diagnosis and risk prediction. Despite significant progress, challenges such as dataset size, data quality, and model validation need to be addressed to maximise the potential of this technology in clinical practice.

Author Biographies

Rosyid R. Al-Hakim, IPB University

Primatology Study Program, Graduate School

Yurii Prokopchuk, Pridneprovsk State Academy of Civil Engineering and Architecture

Department of Computer Science, Information Technologies and Applied Mathematics

References

I. Serdaliyeva, A. Omirbayeva, N. Nurmanova, K. Kenzheyeva, and G. Izzatullayeva, “Propedeutics and Problems of Internal Diseases,”Acta Informatica Medica, vol. 31, no. 4, p. 287, 2023, doi: 10.5455/aim.2023.31.287-291.

V. Suzan and H. Yavuzer, "A Fuzzy Dematel Method To Evaluate The Most Common Diseases In Internal Medicine,"International Journal of Fuzzy Systems, vol. 22, no. 7, pp. 2385–2395, Oct. 2020, doi: 10.1007/s40815-020-00921-x.

R. Alanazi, "Identification and Prediction of Chronic Diseases Using Machine Learning Approach,"J Healthc Eng, vol. 2022, 2022, doi: 10.1155/2022/2826127.

B. Mahesh, "Machine Learning Algorithms-A Review," International Journal of Science and Research, 2020, doi: 10.21275/ART20203995.

Y. Wu, L. Li, B. Xin, Q. Hu, X. Dong, and Z. Li, "Application of machine learning in personalised medicine," Intelligent Pharmacy, vol. 1, no. 3, pp. 152–156, Oct. 2023, doi: 10.1016/j.ipha.2023.06.004.

JAM Sidey-Gibbons and CJ Sidey-Gibbons, "Machine learning in medicine: a practical introduction," BMC Med Res Methodol, vol. 19, no. 1, March. 2019, doi: 10.1186/s12874-019-0681-4.

G. Battineni, GG Sagaro, N. Chinatalapudi, and F. Amenta, "Applications of Machine Learning Predictive Models in the Chronic Disease Diagnosis," J Pers Med, vol. 10, no. 2, p. 21, March. 2020, doi: 10.3390/jpm10020021.

CK Gomathy and A. Rohith Naidu Sri Chandrasekharendra Saraswathi Viswa Mahavidyalaya, "The Prediction Of Disease Using Machine Learning," International Journal of Scientific Research in Engineering and Management, 2021, [Online]. Available: www.ijsrem.com

[9] MM Ahsan, SA Luna, and Z. Siddique, "Machine-Learning-Based Disease Diagnosis: A Comprehensive Review," Healthcare (Switzerland), vol. 10, no. 3. MDPI, Mar. 01, 2022. doi: 10.3390/healthcare10030541.

[10] T. Venu Gopal and A. Sneha, "Heart Disease Prediction Using Machine Learning Techniques Email: drtv.gopal@jntuh.ac.in ," vol. 13, p. 7, 2023.

H. Jindal, S. Agrawal, R. Khera, R. Jain, and P. Nagrath, "Heart disease prediction using machine learning algorithms," inIOP Conference Series: Materials Science and Engineering, IOP Publishing Ltd, Jan. 2021. doi: 10.1088/1757-899X/1022/1/012072.

MA Islam, MZH Majumder, and MA Hussein, "Chronic kidney disease prediction based on machine learning algorithms,"J Pathol Inform, vol. 14, Jan. 2023, doi: 10.1016/j.jpi.2023.100189.

P. Chittoraet al., "Prediction of Chronic Kidney Disease - A Machine Learning Perspective," IEEE Access, vol. 9. Institute of Electrical and Electronics Engineers Inc., pp. 17312–17334, 2021. doi: 10.1109/ACCESS.2021.3053763.

DAP Delzell, S. Magnuson, T. Peter, M. Smith, and BJ Smith, "Machine Learning and Feature Selection Methods for Disease Classification With Application to Lung Cancer Screening Image Data," Front Oncol, vol. 9, Dec. 2019, doi: 10.3389/fonc.2019.01393.

H. Barneset al., "Machine learning in radiology: the new frontier in interstitial lung diseases," The Lancet Digital Health, vol. 5, no. 1. Elsevier Ltd, pp. e41–e50, Jan. 01, 2023. doi: 10.1016/S2589-7500(22)00230-8.

J. Monsi, J. Saji, K. Vinod, L. Joy, and JJ Mathew, "XRAY AI: Lung Disease Prediction Using Machine Learning," International Journal of Information Systems and Computer Sciences, vol. 8, no. 2, pp. 51–54, Apr. 2019, doi: 10.30534/ijiscs/2019/12822019.

A. Bakrania, N. Joshi, X. Zhao, G. Zheng, and M. Bhat, "Artificial intelligence in liver cancers: Decoding the impact of machine learning models in clinical diagnosis of primary liver cancers and liver cancer metastases," Pharmacol Res, vol. 189, March. 2023, doi: 10.1016/j.phrs.2023.106706.

S. Sassanarakkit, S. Hadpech, and V. Thongboonkerd, "Theranostic role of machine learning in clinical management of kidney stone disease,"Comput Struct Biotechnol J, vol. 21, pp. 260–266, 2022, doi: 10.1016/j.csbj.2022.12.004.

SL Cichosz, MH Jensen, O. Hejlesen, SD Henriksen, AM Drewes, and SS Olesen, "Prediction of pancreatic cancer risk in patients with new-onset diabetes using a machine learning approach based on routine biochemical parameters; Prediction of Pancreatic Cancer Risk in New Onset Diabetes," Comput Methods Programs Biomed, vol. 244, Feb. 2024, doi: 10.1016/j.cmpb.2023.107965.

JP Li, AU Haq, SU Din, J. Khan, A. Khan, and A. Saboor, "Heart Disease Identification Method Using Machine Learning Classification in E-Healthcare,"IEEE Access, vol. 8, pp. 107562–107582, 2020, doi: 10.1109/ACCESS.2020.3001149.

G. Manikandan, B. Pragadeesh, V. Manojkumar, AL Karthikeyan, R. Manikandan, and AH Gandomi, "Classification models combined with Boruta feature selection for heart disease prediction," Inform Med Unlocked, vol. 44, p. 101442, 2023, doi: 10.1016/j.imu.2023.101442.

S. Mohapatra, S. Maneesha, PK Patra, and S. Mohanty, "Heart Diseases Prediction based on Stacking Classifiers Model,"Procedia Comput Sci, vol. 218, pp. 1621–1630, 2023, doi: 10.1016/j.procs.2023.01.140.

J. Qezelbash-Chamak, S. Badamchizadeh, K. Eshghi, and Y. Asadi, "A survey of machine learning in kidney disease diagnosis," Machine Learning with Applications, vol. 10, p. 100418, Dec. 2022, doi: 10.1016/j.mlwa.2022.100418.

[24] AL Ammirati, "Chronic Kidney Disease,"Rev Assoc Med Bras, vol. 66, no. suppl 1, pp. s03–s09, 2020, doi: 10.1590/1806-9282.66.s1.3.

TK Chen, DH Knicely, and ME Grams, "Chronic Kidney Disease Diagnosis and Management," JAMA, vol. 322, no. 13, p. 1294, Oct. 2019, doi: 10.1001/jama.2019.14745.

W. Zhong, X. Zhang, Y. Zeng, D. Lin, and J. Wu, "Recent applications and strategies in nanotechnology for lung diseases," Nano Res, vol. 14, no. 7, pp. 2067–2089, Jul. 2021, doi: 10.1007/s12274-020-3180-3.

S. Bharati, P. Podder, and MRH Mondal, "Hybrid deep learning for detecting lung diseases from X-ray images," Inform Med Unlocked, vol. 20, p. 100391, 2020, doi: 10.1016/j.imu.2020.100391.

C. Konget al., "Machine Learning Classifier for Preoperative Prediction of Early Recurrence After Bronchial Arterial Chemoembolization Treatment in Lung Cancer Patients," Acad Radiol, vol. 30, no. 12, pp. 2880–2893, Dec. 2023, doi: 10.1016/j.acra.2023.04.011.

SK Asrani, H. Devarbhavi, J. Eaton, and PS Kamath, "Burden of liver diseases in the world," Journal of Hepatology, vol. 70, no. 1. Elsevier B.V., pp. 151–171, Jan. 01, 2019. doi: 10.1016/j.jhep.2018.09.014.

[30] R. Loomba, SL Friedman, and GI Shulman, "Mechanisms and disease consequences of non-alcoholic fatty liver disease," Cell, vol. 184, no. 10, pp. 2537–2564, May 2021, doi: 10.1016/j.cell.2021.04.015.

K. Pafili and M. Roden, "Non-alcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans,"Mol Metab, vol. 50, p. 101122, Aug. 2021, doi: 10.1016/j.molmet.2020.101122.

PS Asih, Y. Azhar, GW Wicaksono, and DR Akbi, "Interpretable Machine Learning Model For Heart Disease Prediction,"Procedia Comput Sci, vol. 227, pp. 439–445, 2023, doi: 10.1016/j.procs.2023.10.544.

M. Harsha Vardhan, M. Rajesh Kumar, M. Vardhini, S. Leela Varalakshmi, and M. Kumar, "Heart Disease Prediction Using Machine Learning," 2023. [Online]. Available: https://jespublication.com/

Y. Huanget al., "Using a machine learning-based risk prediction model to analyse the coronary artery calcification score and predict coronary heart disease and risk assessment," Comput Biol Med, vol. 151, p. 106297, Dec. 2022, doi: 10.1016/j.compbiomed.2022.106297.

G. Manikandan, B. Pragadeesh, V. Manojkumar, AL Karthikeyan, R. Manikandan, and AH Gandomi, "Classification models combined with Boruta feature selection for heart disease prediction," Inform Med Unlocked, vol. 44, p. 101442, 2024, doi: 10.1016/j.imu.2023.101442.

Md. A. Islam, Md. ZH Majumder, and Md. A. Hussein, "Chronic kidney disease prediction based on machine learning algorithms," J Pathol Inform, vol. 14, p. 100189, 2023, doi: 10.1016/j.jpi.2023.100189.

Md. Mustafizur Rahman, Md. Al-Amin, and J. Hossain, "Machine learning models for chronic kidney disease diagnosis and prediction," Biomed Signal Process Control, vol. 87, p. 105368, Jan. 2024, doi: 10.1016/j.bspc.2023.105368.

B. Khan, R. Naseem, F. Muhammad, G. Abbas, and S. Kim, "An Empirical Evaluation of Machine Learning Techniques for Chronic Kidney Disease Prophecy," IEEE Access, vol. 8, pp. 55012–55022, 2020, doi: 10.1109/ACCESS.2020.2981689.

Y. Li, X. Wu, P. Yang, G. Jiang, and Y. Luo, "Machine Learning for Lung Cancer Diagnosis, Treatment, and Prognosis," Genomics Proteomics Bioinformatics, vol. 20, no. 5, pp. 850–866, Oct. 2022, doi: 10.1016/j.gpb.2022.11.003.

H. Barneset al., "Machine learning in radiology: the new frontier in interstitial lung diseases," Lancet Digit Health, vol. 5, no. 1, pp. e41–e50, Jan. 2023, doi: 10.1016/S2589-7500(22)00230-8.

B. Huanget al., "Prediction of lung malignancy progression and survival with machine learning based on pretreatment FDG-PET/CT," EBioMedicine, vol. 82, p. 104127, Aug. 2022, doi: 10.1016/j.ebiom.2022.104127.

FJM Shamrat, S. Azam, A. Karim, K. Ahmed, FM Bui, and F. De Boer, "High-precision multiclass classification of lung disease through customised MobileNetV2 from chest X-ray images,"Comput Biol Med, vol. 155, p. 106646, Mar. 2023, doi: 10.1016/j.compbiomed.2023.106646.

S. Rahman, FM Javed, M. Shamrat, Z. Tasnim, J. Roy, and SA Hossain, "A Comparative Study On Liver Disease Prediction Using Supervised Machine Learning Algorithms," International Journal Of Scientific & Technology Research, vol. 8, no. 11, 2019, [Online]. Available: www.ijstr.org

S. Skurzaket al., "A simple machine learning-derived rule to promote ERAS pathways in Liver Transplantation," Journal of Liver Transplantation, vol. 12, p. 100179, Nov. 2023, doi: 10.1016/j.liver.2023.100179.

J. Singh, S. Bagga, and R. Kaur, "Software-based Prediction of Liver Disease with Feature Selection and Classification Techniques," Procedia Comput Sci, vol. 167, pp. 1970–1980, 2020, doi: 10.1016/j.procs.2020.03.226.

C. Chakraborty, M. Bhattacharya, S. Pal, and S.-S. Lee, "From machine learning to deep learning: Advances of the recent data-driven paradigm shift in medicine and healthcare," Curr Res Biotechnol, vol. 7, p. 100164, 2024, doi: 10.1016/j.crbiot.2023.100164.

A. Javaidet al., "Medicine 2032: The future of cardiovascular disease prevention with machine learning and digital health technology," Am J Prev Cardiol, vol. 12, p. 100379, Dec. 2022, doi: 10.1016/j.ajpc.2022.100379.

AM Alaa, T. Bolton, E. Di Angelantonio, J. H. F. Rudd, and M. van der Schaar, "Cardiovascular disease risk prediction using automated machine learning: A prospective study of 423,604 UK Biobank participants," PLOS One, vol. 14, no. 5, p. e0213653, May 2019, doi: 10.1371/journal.pone.0213653.

KY Ngiam and IW Khor, "Big data and machine learning algorithms for healthcare delivery," Lancet Oncol, vol. 20, no. 5, pp. e262–e273, May 2019, doi: 10.1016/S1470-2045(19)30149-4.

A. Alanazi, "Using machine learning for healthcare challenges and opportunities," Inform Med Unlocked, vol. 30, p. 100924, 2022, doi: 10.1016/j.imu.2022.100924.

K. Rasheed, A. Qayyum, M. Ghaly, A. Al-Fuqaha, A. Razi, and J. Qadir, "Explainable, trustworthy, and ethical machine learning for healthcare: A survey," Comput Biol Med, vol. 149, p. 106043, Oct. 2022, doi: 10.1016/j.compbiomed.2022.106043.

Downloads

Published

2025-01-26

How to Cite

Al-Hakim, R., & Prokopchuk, Y. (2025). Predicting internal diseases in humans using machine learning: A systematic literature review. Journal of Advanced Health Informatics Research, 2(1), 50–63. https://doi.org/10.59247/jahir.v2i1.195

Issue

Section

Articles